Artificial elimination of drug resistance from group A beta-hemolytic streptococci.

نویسندگان

  • M Nakae
  • M Inoue
  • S Mitsuhashi
چکیده

Ten strains of beta-hemolytic streptococci were tested for elimination of resistance to macrolide antibiotics, tetracycline, and chloramphenicol. Six of the strains lost resistance after cultivation at 41 C or addition of acriflavine (0.2 mug/ml). These results suggest that determinants governing resistance to these antibiotics are located on extrachromosomal genetic elements (plasmids) that are widely distributed in streptococci.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 7 5  شماره 

صفحات  -

تاریخ انتشار 1975